H5P. This tool (website) provides a framework for creating interactive web content. It is free and open-source. Click here to see examples of the types of content that may be created. H5P.org recently announced the availability of a plugin to be able to use these tools inside of Moodle. The plugin installs into Moodle as an activity, meaning that it may be used in every context in which other activities may be used. As with activities, they may be graded.
One of the tools available within H5P is an interactive video. Below is an example:
This tool allows an instructor to paste in a URL from a YouTube video and then layer questions on top of the original video. there are choices about how the questions appear and whether or not the video should pause while the question appears. There are a number of question types.
It remains to be seen how accessible all of these tools are but it appears that making this suite of tools as accessible as possible is a goal of the developer. We will be experimenting with it more over the semester and share any possible updates.